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  • Writer's pictureDr. Roisin O'Loughlin

Premature Ovarian Insufficency (POI) or Premature menopause

POI or premature menopause is when the ovaries stop functioning under the age of 40.


It is relatively common condition with an incidence of 1:100 in those under 40, 1:1000 in women under 30 and 1:10,000 in women under 20 years old.


What are the causes of POI?

  • Unknown (Idiopathic)

  • Genetic (Positive family history)

  • Autoimmune diseases such as thyroid dysfunction or Diabetes Mellitus

  • Infection

  • Surgery

  • Cancer treatment

What are the symptoms of POI?

  • Irregular periods or cessation of periods

  • Peri-menopausal or menopausal symptoms such as; hot flashes, night sweats, mood disturbance, difficulty sleeping, joint pains, headaches and lowered libido

  • Difficulty getting pregnant

What tests can you do to diagnose POI?

  • FSH (Follicle Stimulating Hormone)- An FSH level of > 30 on 2 occasions alongside clinical symptoms of POI can confirm the condition

  • AMH (Anti-Mullerian Hormone)- low level/undetectable

Where can you access help if you think you may have POI?

  • At TheFertilityHQ, we can carry out these tests if you think you may be at risk of POI or having fertility issues

  • Your GP



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